MolNFT v1 · #12165 · protein
Solution structure of the lipoic acid-bearing domain of the E2 component of human, mitochondrial branched-chain alpha-ketoacid dehydrogenase
1K8O · E2 component of branched-chain alpha-ketoacid dehydrogenase: “Solution structure of the lipoic acid-bearing domain of the E2 component of human, mitochondrial…”. Solution nmr, 1 pocket (best druggability 0.56). MolNFT v1 #12165 on…
- PDB
- 1K8O
- Type
- protein
- Length
- 87 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- E2 component of branched-chain alpha-ketoacid dehydrogenase
- EC
- 2.3.1.-
- UniProt
- P11182
- Pockets
- 1 · best druggability 0.56
Structure
solution nmr · 1 distinct chain · 0% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E2 component of branched-chain alpha-ketoacid dehydrogenase (EC 2.3.1.-) | protein | 87 | 0% helix, 34% strand | P11182 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 147 | 0.56 | 0.82 | 20 | empty |
Compared structures
- 1K8O · Solution Structure of the Lipoic Acid-Bearing Domain of the E2 component of Human… · the same entry in another collection · chain A against A, TM-score 1.00
- P11182 · AlphaFold monomer V2.0 prediction for lipoamide acyltransferase component of… · a predicted model of the same protein · chain A against A, TM-score 0.63
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11182
- Elsewhere: RCSB PDB 1K8O · PDBe 1K8O · UniProt P11182
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