MolNFT v1 · #121424 · protein

Human LTC4S mutant-S36E

5HV9 · Leukotriene C4 synthase: “Human LTC4S mutant-S36E”. X-ray diffraction, 2 ligands (GSH, SO4). MolNFT v1 #121424 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5HV9
Type: protein
Length: 143 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Leukotriene C4 synthase
EC: 4.4.1.20
UniProt: Q16873
Ligands: GSH, SO4

Structure

x-ray diffraction · 1 distinct chain · 80% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Leukotriene C4 synthase (EC 4.4.1.20)	protein	143	80% helix, 0% strand	Q16873

Ligands and binding sites

GSH · Glutathione · ligand · chains A
SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5HV9 · Human LTC4S mutant-S36E · the same entry in another collection · chain A against A, TM-score 1.00
Q16873 · AlphaFold monomer V2.0 prediction for leukotriene C4 synthase (Q16873) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q16873
Elsewhere: RCSB PDB 5HV9 · PDBe 5HV9 · UniProt Q16873

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