MolNFT v1 · #120604 · protein

Crystal structure of myelin-gene regulatory factor DNA binding domain

5H5P · Myelin regulatory factor: “Crystal structure of myelin-gene regulatory factor DNA binding domain”. X-ray diffraction, 1 pocket (best druggability 0.31). MolNFT v1 #120604 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5H5P
Type: protein
Length: 184 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myelin regulatory factor
UniProt: Q3UR85
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 1 distinct chain · 2% helix, 56% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Myelin regulatory factor	protein	184	2% helix, 56% strand	Q3UR85

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.31	0.77	11	empty

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

5H5P · Crystal structure of Myelin-gene Regulatory Factor DNA binding domain · the same entry in another collection · chain A against A, TM-score 1.00
Q3UR85 · AlphaFold monomer V2.0 prediction for myelin regulatory factor (Q3UR85) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q3UR85
Elsewhere: RCSB PDB 5H5P · PDBe 5H5P · UniProt Q3UR85

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