MolNFT v1 · #255787 · protein

AlphaFold monomer V2.0 prediction for myelin regulatory factor (Q3UR85)

Q3UR85: “AlphaFold monomer V2.0 prediction for myelin regulatory factor (Q3UR85)”. 6 pockets (best druggability 0.61). MolNFT v1 #255787 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q3UR85
Type: protein
Length: 1,138 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
Molecule: Myelin regulatory factor
UniProt: Q3UR85
Pockets: 6 · best druggability 0.61

Structure

1 distinct chain · 13% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Myelin regulatory factor	protein	1138	13% helix, 18% strand	Q3UR85

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	556	0.61	0.74	43	empty
2	236	0.49	0.74	24	empty
3	154	0.48	0.77	24	empty
4	73	0.35	0.76	18	empty
5	61	0.32	0.76	20	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

5H5P · Crystal structure of Myelin-gene Regulatory Factor DNA binding domain · an experimental structure of the same protein · chain A against A, TM-score 0.16
5H5P · Crystal structure of myelin-gene regulatory factor DNA binding domain · an experimental structure of the same protein · chain A against A, TM-score 0.16
7DC3 · Crystal structure of the myrf ica domain · an experimental structure of the same protein · chain A against A, TM-score 0.13

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q3UR85
Elsewhere: UniProt Q3UR85 · AlphaFold DB Q3UR85

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