MolNFT v1 · #119811 · protein

Catalytic domain of tetrahymena GCN5 histone acetyltransferase in complex with coenzyme a

5GCN · Histone acetyltransferase GCN5: “Catalytic domain of tetrahymena GCN5 histone acetyltransferase in complex with coenzyme a”. Solution nmr, 1 ligand (COA), 1 pocket (best druggability 0.56). MolNFT v1 #119811 on GenesisL1: 3D…

PDB: 5GCN
Type: protein
Length: 166 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Histone acetyltransferase GCN5
UniProt: Q27198
Ligands: COA
Pockets: 1 · best druggability 0.56

Structure

solution nmr · 1 distinct chain · 33% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Histone acetyltransferase GCN5	protein	166	33% helix, 21% strand	Q27198

Ligands and binding sites

COA · Coenzyme A · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	167	0.56	0.80	21	COA

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q27198
Elsewhere: RCSB PDB 5GCN · PDBe 5GCN · UniProt Q27198

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