MolNFT v1 · #119557 · protein

Structure of the dispase autolysis inducing protein from streptomyces mobaraensis

5FZP · Dispase autolysis-inducing protein: “Structure of the dispase autolysis inducing protein from streptomyces mobaraensis”. X-ray diffraction, 1 ligand (CA), 2 pockets (best druggability 0.86). MolNFT v1 #119557 on GenesisL1: 3D…

PDB: 5FZP
Type: protein
Length: 685 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dispase autolysis-inducing protein
UniProt: P84908
Ligands: CA
Pockets: 2 · best druggability 0.86

Structure

x-ray diffraction · 2 distinct chains · 1% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dispase autolysis-inducing protein	protein	344	1% helix, 45% strand	P84908
B	Dispase autolysis-inducing protein	protein	341	1% helix, 46% strand	P84908

Ligands and binding sites

CA · Calcium ion · metal · 4 copies · chains A, B
GOL · Glycerol · additive · 7 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	989	0.86	0.86	94	empty
2	830	0.84	0.87	73	empty

Interfaces

1 interface between chains.

A–B · 1226 Å² buried · 13 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

5FZP · Structure of the dispase autolysis inducing protein from Streptomyces mobaraensis · the same entry in another collection · chain A against A, TM-score 1.00
P84908 · AlphaFold monomer V2.0 prediction for dispase autolysis-inducing protein (P84908) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P84908
Elsewhere: RCSB PDB 5FZP · PDBe 5FZP · UniProt P84908

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