MolNFT v1 · #119369 · protein

The complexity of the ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition

5FU2 · CBM74-RFGH5: “The complexity of the ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition”. X-ray diffraction, 3 ligands (BMA, NA, CA), 1 pocket (best druggability 0.53). MolNFT v1 #119369 on GenesisL1…

PDB: 5FU2
Type: protein
Length: 193 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CBM74-RFGH5
Ligands: BMA, NA, CA
Pockets: 1 · best druggability 0.53

Structure

x-ray diffraction · 2 distinct chains · 3% helix, 63% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CBM74-RFGH5	protein	97	3% helix, 63% strand	—
B	CBM74-RFGH5	protein	96	3% helix, 64% strand	—

Ligands and binding sites

BMA · beta-D-mannopyranose · sugar · 11 copies · chains A, B
NA · Sodium ion · metal · 3 copies · chains B
CA · Calcium ion · metal · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	235	0.53	0.77	33	empty

Interfaces

1 interface between chains.

A–B · 353 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

5FU2 · The complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 5FU2 · PDBe 5FU2

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