MolNFT v1 · #119345 · protein
Crystal structure of PIF1 helicase from bacteroides in complex with ADP
5FTC · Tpr domain protein: “Crystal structure of PIF1 helicase from bacteroides in complex with ADP”. X-ray diffraction, 2 ligands (ADP, CA), 4 pockets (best druggability 0.81). MolNFT v1 #119345 on GenesisL1: 3D structure, binding sites…
- PDB
- 5FTC
- Type
- protein
- Length
- 431 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tpr domain protein
- EC
- 3.6.4.12
- UniProt
- D7K0H3
- Ligands
- ADP, CA
- Pockets
- 4 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tpr domain protein (EC 3.6.4.12) | protein | 431 | 32% helix, 25% strand | D7K0H3 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1089 | 0.81 | 0.82 | 116 | ADP, CA |
| 2 | 299 | 0.68 | 0.83 | 48 | empty |
| 3 | 115 | 0.45 | 0.78 | 26 | empty |
| 4 | 55 | 0.33 | 0.78 | 19 | empty |
Compared structures
- 5FTC · Crystal structure of Pif1 helicase from Bacteroides in complex with ADP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D7K0H3
- Elsewhere: RCSB PDB 5FTC · PDBe 5FTC · UniProt D7K0H3
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