MolNFT v1 · #119069 · protein

Structure of E.COLI inducible lysine decarboxylase at active pH

5FKX · Lysine decarboxylase, inducible: “Structure of E.COLI inducible lysine decarboxylase at active pH”. Electron microscopy, 10 pockets (best druggability 0.80). MolNFT v1 #119069 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 5FKX
Type: protein
Length: 710 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lysine decarboxylase, inducible
EC: 4.1.1.18
UniProt: P0A9H3
Pockets: 10 · best druggability 0.80

Structure

electron microscopy · 1 distinct chain · 42% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lysine decarboxylase, inducible (EC 4.1.1.18)	protein	710	42% helix, 16% strand	P0A9H3

Pockets

10 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	749	0.80	0.84	111	empty
2	579	0.72	0.80	72	empty
3	412	0.70	0.82	59	empty
4	610	0.66	0.76	54	empty
5	505	0.65	0.77	51	empty

Compared structures

5FKX · Structure of E.coli inducible lysine decarboxylase at active pH · the same entry in another collection · chain A against A, TM-score 1.00
P0A9H3 · AlphaFold monomer V2.0 prediction for inducible lysine decarboxylase (P0A9H3) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A9H3
Elsewhere: RCSB PDB 5FKX · PDBe 5FKX · UniProt P0A9H3

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