MolNFT v1 · #118354 · protein

Chicken prestin stas domain

5EZB · Chicken prestin stas DOMAIN,CHICKEN prestin stas domain: “Chicken prestin stas domain”. X-ray diffraction, 3 ligands (OXL, ZN, NA), 1 pocket (best druggability 0.58). MolNFT v1 #118354 on GenesisL1: 3D structure, binding sites and…

PDB: 5EZB
Type: protein
Length: 276 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chicken prestin stas DOMAIN,CHICKEN prestin stas domain
UniProt: A0FKN5
Ligands: OXL, ZN, NA
Pockets: 1 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Chicken prestin stas DOMAIN,CHICKEN prestin stas domain	protein	138	36% helix, 22% strand	A0FKN5

Ligands and binding sites

OXL · Oxalate ion · ligand · chains B
ZN · Zinc ion · metal · 2 copies · chains A, B
NA · Sodium ion · metal · chains A, B
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	305	0.58	0.77	45	NA

Interfaces

1 interface between chains.

A–B · 378 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

5EZB · Chicken prestin STAS domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0FKN5
Elsewhere: RCSB PDB 5EZB · PDBe 5EZB · UniProt A0FKN5

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