MolNFT v1 · #117829 · protein

Crystal structure of chromobox homolog 7 (CBX7) chromodomain with MS351

5EJW · Chromobox protein homolog 7: “Crystal structure of chromobox homolog 7 (CBX7) chromodomain with MS351”. X-ray diffraction, 1 ligand (5PZ), 1 pocket (best druggability 0.43). MolNFT v1 #117829 on GenesisL1: 3D structure, binding…

PDB: 5EJW
Type: protein
Length: 80 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chromobox protein homolog 7
UniProt: Q8VDS3
Ligands: 5PZ
Pockets: 1 · best druggability 0.43

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chromobox protein homolog 7	protein	80	29% helix, 30% strand	Q8VDS3

Ligands and binding sites

5PZ · (1~{R})-2-[2-azanylidene-3-[(2-methylphenyl)methyl]benzimidazol-1-yl]-1-(3,4-dichlorophenyl)ethanol · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	117	0.43	0.76	20	empty

Compared structures

5EJW · Crystal structure of chromobox homolog 7 (CBX7) chromodomain with MS351 · the same entry in another collection · chain A against A, TM-score 1.00
Q8VDS3 · AlphaFold monomer V2.0 prediction for chromobox protein homolog 7 (Q8VDS3) · a predicted model of the same protein · chain A against A, TM-score 0.77

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8VDS3
Elsewhere: RCSB PDB 5EJW · PDBe 5EJW · UniProt Q8VDS3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.