MolNFT v1 · #117792 · protein
Mini TRIM5 B-box 2 dimer C2 crystal form
5EIU · Trim protein-E3 ligase chimera: “Mini TRIM5 B-box 2 dimer C2 crystal form”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #117792 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5EIU
- Type
- protein
- Length
- 266 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Trim protein-E3 ligase chimera
- EC
- 6.3.2.-
- UniProt
- Q0PF16, P34945
- Ligands
- ZN
Structure
x-ray diffraction · 2 distinct chains · 69% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Trim protein-E3 ligase chimera (EC 6.3.2.-) | protein | 134 | 70% helix, 8% strand | Q0PF16, P34945 |
| D | Trim protein-E3 ligase chimera (EC 6.3.2.-) | protein | 132 | 68% helix, 8% strand | Q0PF16, P34945 |
Ligands and binding sites
- ZN · Zinc ion · metal · 4 copies · chains A, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–D · 467 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 5EIU · Mini TRIM5 B-box 2 dimer C2 crystal form · the same entry in another collection · chain A against A, TM-score 1.00
- P34945 · AlphaFold monomer V2.0 prediction for serine--tRNA ligase (P34945) · a predicted model of the same protein · chain D against A, TM-score 0.54
- Q0PF16 · AlphaFold monomer V2.0 prediction for tripartite motif-containing protein 5 (Q0PF16) · a predicted model of the same protein · chain D against A, TM-score 0.40
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0PF16
- Every structure of UniProt P34945
- Elsewhere: RCSB PDB 5EIU · PDBe 5EIU · UniProt Q0PF16 · UniProt P34945
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