MolNFT v1 · #117608 · protein
Human fatty acid binding protein 4 in complex with 6-chloro-2-methyl- 4-phenyl-quinoline-3-carboxylic acid at 1.18A
5EDB · Fatty acid-binding protein, adipocyte: “Human fatty acid binding protein 4 in complex with 6-chloro-2-methyl- 4-phenyl-quinoline-3-carboxylic acid at…”. X-ray diffraction, 1 ligand (5M8), 1 pocket (best druggability 0.84). MolNFT v1…
- PDB
- 5EDB
- Type
- protein
- Length
- 134 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fatty acid-binding protein, adipocyte
- UniProt
- P15090
- Ligands
- 5M8
- Pockets
- 1 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 15% helix, 57% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fatty acid-binding protein, adipocyte | protein | 134 | 15% helix, 57% strand | P15090 |
Ligands and binding sites
- 5M8 · 6-chloranyl-2-methyl-4-phenyl-quinoline-3-carboxylic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 282 | 0.84 | 0.95 | 33 | 5M8 |
Compared structures
- 5EDB · human fatty acid binding protein 4 in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- P15090 · AlphaFold monomer V2.0 prediction for fatty acid-binding protein, adipocyte (P15090) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15090
- Elsewhere: RCSB PDB 5EDB · PDBe 5EDB · UniProt P15090
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