UniProt P15090
Fatty acid-binding protein, adipocyte (P15090)
Fatty acid-binding protein, adipocyte (UniProt P15090): 83 experimental structures and 1 predicted model on GenesisL1, 38 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P15090
- Protein
- Fatty acid-binding protein, adipocyte
- Experimental structures
- 83
- Predicted models
- 1
- Ligands
- 38
- Pockets
- 4 · 4 records with a druggable one
Structures
84 records of P15090 in the MolNFT archive: 83 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1TOU | Crystal structure of human adipocyte fatty acid binding protein in complex with a non-covalent… | x-ray diffraction | A | — | — |
| 1TOU | Crystal structure of human adipocyte fatty acid binding protein in complex with a non-covalent… | x-ray diffraction | A | — | — |
| 1TOW | Crystal structure of human adipocyte fatty acid binding protein in complex with a carboxylic acid… | x-ray diffraction | A | — | — |
| 1TOW | Crystal structure of human adipocyte fatty acid binding protein in complex with a carboxylic acid… | x-ray diffraction | A | — | — |
| 2HNX | Crystal Structure of aP2 | x-ray diffraction | A | — | — |
| 2HNX | Crystal structure of AP2 | x-ray diffraction | A | — | — |
| 2NNQ | Crystal structure of human adipocyte fatty acid binding protein in complex with… | x-ray diffraction | A | — | — |
| 2NNQ | Crystal structure of human adipocyte fatty acid binding protein in complex with… | x-ray diffraction | A | — | — |
| 3FR2 | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte Fatty-Acid… | x-ray diffraction | A | — | — |
| 3FR2 | N-benzyl-indolo carboxylic acids: design and synthesis of potent and selective adipocyte fatty-acid… | x-ray diffraction | A | — | — |
| 3FR4 | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte Fatty-Acid… | x-ray diffraction | A | — | — |
| 3FR4 | N-benzyl-indolo carboxylic acids: design and synthesis of potent and selective adipocyte fatty-acid… | x-ray diffraction | A | — | — |
| 3FR5 | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte Fatty-Acid… | x-ray diffraction | A | — | — |
| 3FR5 | N-benzyl-indolo carboxylic acids: design and synthesis of potent and selective adipocyte fatty-acid… | x-ray diffraction | A | — | — |
| 3P6C | Human adipocyte lipid-binding protein FABP4 in complex with citric acid | x-ray diffraction | A | — | — |
| 3P6C | Human adipocyte lipid-binding protein FABP4 in complex with citric acid | x-ray diffraction | A | — | — |
| 3P6D | Human adipocyte lipid-binding protein FABP4 in complex with 3-(4-methoxy-3-methylphenyl) propionic… | x-ray diffraction | A | — | — |
| 3P6D | Human adipocyte lipid-binding protein FABP4 in complex with 3-(4- methoxy-3-methylphenyl) propionic… | x-ray diffraction | A | — | — |
| 3P6E | Human adipocyte lipid-binding protein FABP4 in complex with 3-(4-methoxyphenyl) propionic acid | x-ray diffraction | A | — | — |
| 3P6E | Human adipocyte lipid-binding protein FABP4 in complex with 3-(4- methoxyphenyl) propionic acid | x-ray diffraction | A | — | — |
| 3P6F | Human adipocyte lipid-binding protein FABP4 in complex with (S)-3-phenyl butyric acid | x-ray diffraction | A | — | — |
| 3P6F | Human adipocyte lipid-binding protein FABP4 in complex with (S)-3- phenyl butyric acid | x-ray diffraction | A | — | — |
| 3P6G | Human adipocyte lipid-binding protein FABP4 in complex with (R)-ibuprofen | x-ray diffraction | A | — | — |
| 3P6G | Human adipocyte lipid-binding protein FABP4 in complex with (R)- ibuprofen | x-ray diffraction | A | — | — |
| 3P6H | Human adipocyte lipid-binding protein FABP4 in complex with (S)-ibuprofen | x-ray diffraction | A | — | — |
| 3P6H | Human adipocyte lipid-binding protein FABP4 in complex with (S)- ibuprofen | x-ray diffraction | A | — | — |
| 3Q6L | Crystal Structure of Human Adipocyte Fatty Acid Binding Protein (FABP4) at 1.4 Ang. Resolution | x-ray diffraction | A | — | — |
| 3Q6L | Crystal structure of human adipocyte fatty acid binding protein (FABP4) at 1.4 ang. resolution | x-ray diffraction | A | — | — |
| 3RZY | Human adipocyte lipid-binding protein FABP4, Apo form at 1.08 Ang resolution. | x-ray diffraction | A | — | — |
| 3RZY | Human adipocyte lipid-binding protein FABP4, apo form at 1.08 ang resolution. | x-ray diffraction | A | — | — |
| 4NNS | Crystal structure of FABP4 in complex with novel inhibitor | x-ray diffraction | A | — | — |
| 4NNS | Crystal structure of FABP4 in complex with novel inhibitor | x-ray diffraction | A | — | — |
| 4NNT | Crystal structure of FABP4 in complex with novel inhibitor | x-ray diffraction | A | — | — |
| 4NNT | Crystal structure of FABP4 in complex with novel inhibitor | x-ray diffraction | A | — | — |
| 5D45 | Crystal Structure of FABP4 in complex with 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic… | x-ray diffraction | A | 57P | — |
| 5D45 | Crystal structure of FABP4 in complex with 3-(5-cyclopropyl-2,3- diphenyl-1H-indol-1-YL)PROPANOIC… | x-ray diffraction | A | — | — |
| 5D47 | Crystal Structure of FABP4 in complex with 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-in… | x-ray diffraction | A | L19 | — |
| 5D47 | Crystal structure of FABP4 in complex with 3-[5-cyclopropyl-3-(3… | x-ray diffraction | A | — | — |
| 5D48 | Crystal Structure of FABP4 in complex with 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(p… | x-ray diffraction | A | L96, PO4 | — |
| 5D48 | Crystal structure of FABP4 in complex with 3-{5-cyclopropyl-3-(3,5… | x-ray diffraction | A | — | — |
| 5D4A | Crystal Structure of FABP4 in complex with 3-(2-phenyl-1H-indol-1-yl)propanoic acid | x-ray diffraction | A | 57Q | — |
| 5D4A | Crystal structure of FABP4 in complex with 3-(2-phenyl-1H-indol-1-yl) propanoic acid | x-ray diffraction | A | — | — |
| 5EDB | human fatty acid binding protein 4 in complex with 6-Chloro-2-methyl-4-phenyl-quinoline-3-carboxylic… | x-ray diffraction | A | 5M8 | — |
| 5EDB | Human fatty acid binding protein 4 in complex with 6-chloro-2-methyl… | x-ray diffraction | A | — | — |
| 5EDC | Human FABP4 in complex with 6-chloro-4-phenyl-2-piperidin-1-yl- quinoline-3-carboxylic acid at 1.29A | x-ray diffraction | A | — | — |
| 5HZ6 | FABP4 in complex with 6-Chloro-2-isopropyl-4-(3-isopropyl-phenyl)-quinoline-3-carboxylic acid | x-ray diffraction | A | 65Y | — |
| 5HZ6 | FABP4 in complex with 6-chloro-2-isopropyl-4-(3-isopropyl-phenyl)- quinoline-3-carboxylic acid | x-ray diffraction | A | — | — |
| 5HZ8 | FABP4_3 in complex with 6,8-Dichloro-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid | x-ray diffraction | A | 65Z | — |
| 5HZ8 | FABP4_3 in complex with 6,8-dichloro-4-phenyl-2-piperidin-1-yl- quinoline-3-carboxylic acid | x-ray diffraction | A | — | — |
| 5Y0F | Crystal structure of human FABP4 complexed with ligand… | x-ray diffraction | A | 8JO | 1 (best 0.85) |
| 5Y0F | Crystal structure of human FABP4 complexed with ligand 2-fluoro-5-((4… | x-ray diffraction | A | 8JO | — |
| 5Y0G | Crystal structure of human FABP4 complexed with ligand 4-fluoro-3-((4… | x-ray diffraction | A | 8JL | — |
| 5Y0X | Crystal structure of human FABP4 complexed with ligand 2-fluoro-3-((4… | x-ray diffraction | A | 8JR | — |
| 5Y12 | Crystal structure of human FABP4 complexed with ligand 5-((4… | x-ray diffraction | A | 8JX | — |
| 5Y13 | Crystal structure of human FABP4 complexed with ligand 5-((4… | x-ray diffraction | A | 8K0 | — |
| 6AYL | Human adipocyte lipid-binding protein FABP4 in complex with fluorescein | x-ray diffraction | A | FLU | — |
| 6LJS | Crystal structure of human FABP4 in complex with a novel inhibitor | x-ray diffraction | A | EHR | — |
| 6LJT | Crystal structure of human FABP4 in complex with a novel inhibitor | x-ray diffraction | A | EH6 | — |
| 6LJT | Crystal structure of human FABP4 in complex with a novel inhibitor | x-ray diffraction | A | EH6 | — |
| 6LJU | Crystal structure of human FABP4 in complex with a novel inhibitor | x-ray diffraction | A | EHU | — |
24 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 14 records
- EHO · 2-phenylazanylbenzoic acid · in 3 records
- 8JO · 2-fluoranyl-5-[(4-methoxynaphthalen-1-yl) sulfonylamino]benzoic acid · in 2 records
- EH6 · 2-[(3-chloranyl-2-phenyl-phenyl)amino]benzoic acid · in 2 records
- EHC · 2-[[3-chloranyl-2-(2,3-dihydro-1-benzofuran-5-yl) phenyl]amino]benzoic acid · in 2 records
- EHU · 2-[[3-chloranyl-4-(methylamino)-2-phenyl-phenyl]amino]benzoic acid · in 2 records
- 57P · 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic acid · in 1 record
- 57Q · 3-(2-phenyl-1H-indol-1-yl)propanoic acid · in 1 record
- 5M8 · 6-chloranyl-2-methyl-4-phenyl-quinoline-3-carboxylic acid · in 1 record
- 65Y · 6-Chloro-2-isopropyl-4-(3-isopropyl-phenyl)-quinoline-3-carboxylic acid · in 1 record
- 65Z · 6,8-dichloro-4-phenyl-2-(piperidin-1-yl)quinoline-3-carboxylic acid · in 1 record
- 8JL · 4-fluoranyl-3-[(4-methoxynaphthalen-1-yl) sulfonylamino]benzoic acid · in 1 record
- 8JR · 2-fluoranyl-3-[(4-methoxynaphthalen-1-yl) sulfonylamino]benzoic acid · in 1 record
- 8JX · 5-[(4-methoxynaphthalen-1-yl)sulfonylamino]pentanoic acid · in 1 record
- 8K0 · 5-[(4-bromanylnaphthalen-1-yl)sulfonylamino]pentanoic acid · in 1 record
- EHR · 2-[(2-phenylphenyl)amino]benzoic acid · in 1 record
- FBB · 6-fluoro-1,3-benzothiazol-2-amine · in 1 record
- FLU · 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-benzoic acid · in 1 record
- L19 · 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-indol-1-yl]propanoic acid · in 1 record
- L96 · 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy)phenyl]-1H-indol-1-yl}propanoic acid · in 1 record
- NC0 · 2-[(2,3-dihydro-1H-indole-1-carbonyl)amino]benzoic acid · in 1 record
- O9U · 1-[(5-chloro[1,1'-biphenyl]-2-yl)methyl]-4-hydroxy-5,6-dihydropyridin-2(1H)-one · in 1 record
- PLM · Palmitic acid · in 1 record
- PO4 · Phosphate ion · in 1 record
- Q1I · (3P)-6-cyclopentyl-N,5-dimethyl-4-phenyl-N-(propan-2-yl)-3-(1H-tetrazol-5-yl)pyridin-2-amine · in 1 record
- QN6 · (3M)-4-(2-methylpropyl)-2-phenyl-3-(1H-tetrazol-5-yl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine · in 1 record
- R80 · (5S)-6-[(3,4-dichlorophenyl)methyl]-5-methyl-1lambda~6~,2,6-thiadiazinane-1,1,3-trione · in 1 record
- S4I · (3S)-1-[(4-chlorophenyl)methyl]-3-hydroxypyrrolidine-2,4-dione · in 1 record
- SUX · (3P)-2-[(2S)-oxolan-2-yl]-4-phenyl-3-(1H-tetrazol-5-yl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine · in 1 record
- U8H · 6-[(4-methoxyphenyl)methyl]-1,2,4-triazine-3,5(2H,4H)-dithione · in 1 record
Experiment against prediction
- 3FR4 chain A against the predicted model P15090: TM-score 0.99, RMSD 0.43 Å
- 3FR4 chain A against the predicted model P15090: TM-score 0.99, RMSD 0.43 Å
- 4NNT chain A against the predicted model P15090: TM-score 0.97, RMSD 0.45 Å
- 4NNT chain A against the predicted model P15090: TM-score 0.97, RMSD 0.45 Å
- 1TOW chain A against the predicted model P15090: TM-score 0.99, RMSD 0.46 Å
- 1TOW chain A against the predicted model P15090: TM-score 0.99, RMSD 0.46 Å
- 2HNX chain A against the predicted model P15090: TM-score 0.96, RMSD 0.46 Å
- 2HNX chain A against the predicted model P15090: TM-score 0.96, RMSD 0.46 Å
- 4NNS chain A against the predicted model P15090: TM-score 0.97, RMSD 0.47 Å
- 4NNS chain A against the predicted model P15090: TM-score 0.97, RMSD 0.47 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.