MolNFT v1 · #117550 · protein
Crystal structure of ECCB1 of mycobacterium tuberculosis in spacegroup P21 (state IV)
5EBD · Esx-1 secretion system protein ECCB1: “Crystal structure of ECCB1 of mycobacterium tuberculosis in spacegroup P21 (state IV)”. X-ray diffraction, 2 ligands (CA, CL), 2 pockets (best druggability 0.49). MolNFT v1 #117550 on…
- PDB
- 5EBD
- Type
- protein
- Length
- 379 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Esx-1 secretion system protein ECCB1
- UniProt
- P9WNR7
- Ligands
- CA, CL
- Pockets
- 2 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 14% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Esx-1 secretion system protein ECCB1 | protein | 379 | 14% helix, 32% strand | P9WNR7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 68 | 0.49 | 0.84 | 13 | empty |
| 2 | 50 | 0.34 | 0.79 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5EBD · Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P21 (state IV) · the same entry in another collection · chain A against A, TM-score 1.00
- P9WNR7 · AlphaFold monomer V2.0 prediction for esx-1 secretion system ATPase ECCB1 (P9WNR7) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WNR7
- Elsewhere: RCSB PDB 5EBD · PDBe 5EBD · UniProt P9WNR7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.