MolNFT v1 · #11749 · protein
Crystal structure of ribonuclease a (retro-soaked form)
1JVV: “Crystal structure of ribonuclease a (retro-soaked form)”. X-ray diffraction, 4 pockets (best druggability 0.34). MolNFT v1 #11749 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1JVV
- Type
- protein
- Length
- 248 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribonuclease a
- EC
- 3.1.27.5
- UniProt
- P61823
- Pockets
- 4 · best druggability 0.34
Structure
x-ray diffraction · 1 distinct chain · 21% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Ribonuclease a (EC 3.1.27.5) | protein | 124 | 21% helix, 35% strand | P61823 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.34 | 0.77 | 14 | empty |
| 2 | 55 | 0.33 | 0.78 | 14 | empty |
| 3 | 58 | 0.33 | 0.77 | 15 | empty |
| 4 | 52 | 0.24 | 0.72 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 323 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 disulfide (disulfide).
Compared structures
- 1JVV · Crystal structure of ribonuclease a (retro-soaked form) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P61823
- Elsewhere: RCSB PDB 1JVV · PDBe 1JVV · UniProt P61823
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