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MolNFT v1 · #117395 · protein

Re-refinement of the crystal structure of the plexin-semaphorin- integrin DOMAIN/HYBRID DOMAIN/I-EGF1 segment from the human integrin B2 subunit

5E6V · Integrin beta-2: “Re-refinement of the crystal structure of the plexin-semaphorin- integrin DOMAIN/HYBRID DOMAIN/I-EGF1 segment…”. X-ray diffraction, 2 ligands (NAG, FUL). MolNFT v1 #117395 on GenesisL1: 3D structure, binding sites…

PDB
5E6V
Type
protein
Length
224 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Integrin beta-2
UniProt
P05107
Ligands
NAG, FUL

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 40% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AIntegrin beta-2protein22410% helix, 40% strandP05107

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A
  • FUL · beta-L-fucopyranose · sugar

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 9 disulfide, 2 glycan, 1 modified (disulfide, N-glycosylation, cyclization).

Compared structures

  • 5E6V · Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid… · the same entry in another collection · chain A against A, TM-score 1.00
  • P05107 · AlphaFold monomer V2.0 prediction for integrin beta-2 (P05107) · a predicted model of the same protein · chain A against A, TM-score 0.90

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