MolNFT v1 · #11669 · protein

Loop-inserted structure of P1-P1' cleaved ovalbumin mutant R339T

1JTI: “Loop-inserted structure of P1-P1' cleaved ovalbumin mutant R339T”. X-ray diffraction, 6 pockets (best druggability 0.77). MolNFT v1 #11669 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1JTI
Type: protein
Length: 762 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ovalbumin
UniProt: P01012
Pockets: 6 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Ovalbumin	protein	381	28% helix, 36% strand	P01012

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	995	0.77	0.79	94	empty
2	107	0.39	0.76	18	empty
3	80	0.37	0.77	15	empty
4	109	0.35	0.74	17	empty
5	51	0.29	0.76	16	empty

Interfaces

1 interface between chains.

A–B · 1117 Å² buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1JTI · Loop-inserted Structure of P1-P1' Cleaved Ovalbumin Mutant R339T · the same entry in another collection · chain A against A, TM-score 1.00
P01012 · AlphaFold monomer V2.0 prediction for ovalbumin (P01012) · a predicted model of the same protein · chain A against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01012
Elsewhere: RCSB PDB 1JTI · PDBe 1JTI · UniProt P01012

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.