MolNFT v1 · #116514 · protein

Sugar binding protein - human galectin-2 (dimer)

5DG2: “Sugar binding protein - human galectin-2 (dimer)”. X-ray diffraction, 2 ligands (GLC, GAL). MolNFT v1 #116514 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5DG2
Type: protein
Length: 259 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Galectin-2
UniProt: P05162
Ligands: GLC, GAL

Structure

x-ray diffraction · 2 distinct chains · 1% helix, 58% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Galectin-2	protein	128	0% helix, 59% strand	P05162
B	Galectin-2	protein	131	2% helix, 56% strand	P05162

Ligands and binding sites

GLC · alpha-D-glucopyranose · sugar · chains B
GAL · beta-D-galactopyranose · sugar · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 633 Å² buried · 13 hydrogen bonds · protein-protein

Compared structures

5DG2 · Sugar binding protein - human galectin-2 (dimer) · the same entry in another collection · chain A against A, TM-score 1.00
P05162 · AlphaFold monomer V2.0 prediction for galectin-2 (P05162) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05162
Elsewhere: RCSB PDB 5DG2 · PDBe 5DG2 · UniProt P05162

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