MolNFT v1 · #116082 · protein

Crystal structure of tppha variant - H39A

5D2U · Protein serin-threonin phosphatase: “Crystal structure of tppha variant - H39A”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.44). MolNFT v1 #116082 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5D2U
Type: protein
Length: 240 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein serin-threonin phosphatase
UniProt: Q8DGS1
Ligands: CA
Pockets: 1 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein serin-threonin phosphatase	protein	240	32% helix, 28% strand	Q8DGS1

Ligands and binding sites

CA · Calcium ion · metal · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	165	0.44	0.75	30	CA

Compared structures

5D2U · Crystal structure of tPphA Variant - H39A · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8DGS1
Elsewhere: RCSB PDB 5D2U · PDBe 5D2U · UniProt Q8DGS1

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