Crystal structure of the type IX collagen NC2 hetero-trimerization domain with a guest fragment A2A1A1 of type I collagen

Structure

x-ray diffraction · 3 distinct chains · 34% helix, 0% strand (DSSP).

Interfaces

3 interfaces between chains.

• A–C · 1720 Ų buried · 16 hydrogen bonds · protein-protein
• B–C · 1701 Ų buried · 21 hydrogen bonds · protein-protein
• A–B · 1601 Ų buried · 18 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 modified, 1 disulfide (engineered, disulfide).

Compared structures

• 5CTD · Crystal structure of the type IX collagen NC2 hetero-trimerization domain with a guest… · the same entry in another collection · chain B against B, TM-score 1.00
• Q14055 · AlphaFold monomer V2.0 prediction for collagen alpha-2(IX) chain (Q14055) · a predicted model of the same protein · chain B against A, TM-score 0.45
• Q14050 · AlphaFold monomer V2.0 prediction for collagen alpha-3(IX) chain (Q14050) · a predicted model of the same protein · chain C against A, TM-score 0.43
• P20849 · AlphaFold monomer V2.0 prediction for collagen alpha-1(IX) chain (P20849) · a predicted model of the same protein · chain A against A, TM-score 0.41
• P08123 · AlphaFold monomer V2.0 prediction for collagen alpha-2(I) chain (P08123) · a predicted model of the same protein · chain B against A, TM-score 0.37
• P02452 · AlphaFold monomer V2.0 prediction for collagen alpha-1(I) chain (P02452) · a predicted model of the same protein · chain A against A, TM-score 0.32

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P02452
• Every structure of UniProt P20849
• Every structure of UniProt P08123
• Every structure of UniProt Q14055
• Every structure of UniProt Q14050
• Elsewhere: RCSB PDB 5CTD · PDBe 5CTD · UniProt P02452 · UniProt P20849 · UniProt P08123 · UniProt Q14055 · UniProt Q14050