MolNFT v1 · #115536 · protein
Crystal structure of linker-mediated zn-bound human H-ferritin variant 122H-delta C-star
5CMR · Ferritin heavy chain: “Crystal structure of linker-mediated zn-bound human H-ferritin variant 122H-delta C-star”. X-ray diffraction, 3 ligands (BYD, NA, ZN), 1 pocket (best druggability 0.31). MolNFT v1 #115536 on GenesisL1: 3D…
- PDB
- 5CMR
- Type
- protein
- Length
- 173 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferritin heavy chain
- EC
- 1.16.3.1
- UniProt
- P02794
- Ligands
- BYD, NA, ZN
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ferritin heavy chain (EC 1.16.3.1) | protein | 173 | 72% helix, 0% strand | P02794 |
Ligands and binding sites
- BYD · N,N'-dihydroxybenzene-1,4-dicarboxamide · ligand · chains A
- NA · Sodium ion · metal · 3 copies · chains A
- ZN · Zinc ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 54 | 0.31 | 0.76 | 12 | empty |
Compared structures
- 5CMR · Crystal Structure of Linker-Mediated Zn-bound Human H-Ferritin variant 122H-delta C-star · the same entry in another collection · chain A against A, TM-score 1.00
- P02794 · AlphaFold monomer V2.0 prediction for ferritin heavy chain (P02794) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02794
- Elsewhere: RCSB PDB 5CMR · PDBe 5CMR · UniProt P02794
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