MolNFT v1 · #115527 · protein
Gta mutant without mercury - E303D
5CMI · Histo-blood group abo system transferase: “Gta mutant without mercury - E303D”. X-ray diffraction, 4 pockets (best druggability 0.62). MolNFT v1 #115527 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5CMI
- Type
- protein
- Length
- 282 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Histo-blood group abo system transferase
- EC
- 2.4.1.40, 2.4.1.37
- UniProt
- P16442
- Pockets
- 4 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Histo-blood group abo system transferase (EC 2.4.1.40, 2.4.1.37) | protein | 282 | 32% helix, 19% strand | P16442 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 348 | 0.62 | 0.78 | 37 | empty |
| 2 | 67 | 0.47 | 0.84 | 20 | empty |
| 3 | 50 | 0.32 | 0.77 | 14 | empty |
| 4 | 50 | 0.27 | 0.74 | 10 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16442
- Elsewhere: RCSB PDB 5CMI · PDBe 5CMI · UniProt P16442
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