MolNFT v1 · #115465 · protein
CUB1-EGF-CUB2 domains of rat masp-1
5CKQ · Mannan-binding lectin serine protease 1: “CUB1-EGF-CUB2 domains of rat masp-1”. X-ray diffraction, 3 ligands (NAG, CA, NA), 1 pocket (best druggability 0.27). MolNFT v1 #115465 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5CKQ
- Type
- protein
- Length
- 276 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mannan-binding lectin serine protease 1
- EC
- 3.4.21.-
- UniProt
- Q8CHN8
- Ligands
- NAG, CA, NA
- Pockets
- 1 · best druggability 0.27
Structure
x-ray diffraction · 1 distinct chain · 1% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mannan-binding lectin serine protease 1 (EC 3.4.21.-) | protein | 276 | 1% helix, 45% strand | Q8CHN8 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
- CA · Calcium ion · metal · 3 copies · chains A
- NA · Sodium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 64 | 0.27 | 0.73 | 17 | empty |
Modifications
Observed in the structure: 6 disulfide, 2 glycan (disulfide, N-glycosylation).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8CHN8
- Elsewhere: RCSB PDB 5CKQ · PDBe 5CKQ · UniProt Q8CHN8
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