MolNFT v1 · #114990 · protein

Crystal structure of prefusion-stabilized rsv F variant sc-tm

5C6B · Fusion glycoprotein F0,FIBRITIN: “Crystal structure of prefusion-stabilized rsv F variant sc-tm”. X-ray diffraction, 2 ligands (SO4, CL), 3 pockets (best druggability 0.44). MolNFT v1 #114990 on GenesisL1: 3D structure, binding…

PDB: 5C6B
Type: protein
Length: 456 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fusion glycoprotein F0,FIBRITIN
UniProt: P03420, Q38650
Ligands: SO4, CL
Pockets: 3 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
F	Fusion glycoprotein F0,FIBRITIN	protein	456	30% helix, 32% strand	P03420, Q38650

Ligands and binding sites

SO4 · Sulfate ion · ion · 4 copies · chains F
CL · Chloride ion · ion · 2 copies · chains F
NHE · 2-[N-cyclohexylamino]ethane sulfonic acid · additive · chains F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	117	0.44	0.77	17	empty
2	129	0.39	0.74	23	empty
3	58	0.37	0.79	14	empty

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

5C6B · Crystal Structure of Prefusion-stabilized RSV F variant SC-TM · the same entry in another collection · chain F against F, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03420
Every structure of UniProt Q38650
Elsewhere: RCSB PDB 5C6B · PDBe 5C6B · UniProt P03420 · UniProt Q38650

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