MolNFT v1 · #114748 · protein

Crystal structure of the sodium proton antiporter napa in inward- facing conformation

5BZ2 · NA(+)/H(+) antiporter: “Crystal structure of the sodium proton antiporter napa in inward- facing conformation”. X-ray diffraction, 7 pockets (best druggability 0.72). MolNFT v1 #114748 on GenesisL1: 3D structure, binding sites and…

PDB: 5BZ2
Type: protein
Length: 384 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: NA(+)/H(+) antiporter
UniProt: Q72IM4
Pockets: 7 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NA(+)/H(+) antiporter	protein	384	74% helix, 0% strand	Q72IM4

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	551	0.72	0.80	51	empty
2	121	0.53	0.81	27	empty
3	150	0.46	0.76	22	empty
4	64	0.46	0.82	17	empty
5	128	0.46	0.77	27	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q72IM4
Elsewhere: RCSB PDB 5BZ2 · PDBe 5BZ2 · UniProt Q72IM4

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