MolNFT v1 · #114164 · protein

Crystal structure of the C-terminal endonuclease domain of aquifex aeolicus mutl.

5B42 · DNA mismatch repair protein mutl: “Crystal structure of the C-terminal endonuclease domain of aquifex aeolicus mutl.”. X-ray diffraction, 1 ligand (CD), 1 pocket (best druggability 0.40). MolNFT v1 #114164 on GenesisL1: 3D…

PDB: 5B42
Type: protein
Length: 101 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA mismatch repair protein mutl
UniProt: O67518
Ligands: CD
Pockets: 1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein mutl	protein	101	38% helix, 24% strand	O67518

Ligands and binding sites

CD · Cadmium ion · metal · 6 copies · chains A
PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	65	0.40	0.79	12	PEG

Compared structures

5B42 · Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL. · the same entry in another collection · chain A against A, TM-score 1.00
O67518 · AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (O67518) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O67518
Elsewhere: RCSB PDB 5B42 · PDBe 5B42 · UniProt O67518

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