MolNFT v1 · #114089 · protein

Human herpesvirus 6B tegument protein U14

5B1Q · U14 protein: “Human herpesvirus 6B tegument protein U14”. X-ray diffraction, 11 pockets (best druggability 0.86). MolNFT v1 #114089 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5B1Q
Type: protein
Length: 896 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: U14 protein
UniProt: Q9WT50
Pockets: 11 · best druggability 0.86

Structure

x-ray diffraction · 1 distinct chain · 62% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	U14 protein	protein	448	62% helix, 4% strand	Q9WT50

Ligands and binding sites

GOL · Glycerol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

11 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1101	0.86	0.87	62	empty
2	388	0.67	0.80	44	empty
3	377	0.63	0.78	41	empty
4	316	0.59	0.78	48	empty
5	220	0.58	0.80	36	empty

Interfaces

1 interface between chains.

A–B · 4434 Å² buried · 56 hydrogen bonds · protein-protein

Compared structures

5B1Q · Human herpesvirus 6B tegument protein U14 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9WT50
Elsewhere: RCSB PDB 5B1Q · PDBe 5B1Q · UniProt Q9WT50

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