MolNFT v1 · #114052 · protein
Structure of MOEN5-SSO7D fusion protein in complex with beta-decyl maltoside
5B0K · MOEN5,DNA-binding protein 7D: “Structure of MOEN5-SSO7D fusion protein in complex with beta-decyl maltoside”. X-ray diffraction, 8 pockets (best druggability 0.81). MolNFT v1 #114052 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5B0K
- Type
- protein
- Length
- 1,189 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- MOEN5,DNA-binding protein 7D
- UniProt
- A0A010, P39476
- Pockets
- 8 · best druggability 0.81
Structure
x-ray diffraction · 4 distinct chains · 70% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MOEN5,DNA-binding protein 7D | protein | 264 | 77% helix, 0% strand | A0A010, P39476 |
| B | MOEN5,DNA-binding protein 7D | protein | 332 | 65% helix, 9% strand | A0A010, P39476 |
| C | MOEN5,DNA-binding protein 7D | protein | 262 | 77% helix, 0% strand | A0A010, P39476 |
| D | MOEN5,DNA-binding protein 7D | protein | 331 | 64% helix, 10% strand | A0A010, P39476 |
Ligands and binding sites
- DMU · Decyl-beta-D-maltopyranoside · additive · 6 copies · chains A, C, B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1172 | 0.81 | 0.82 | 82 | DMU |
| 2 | 1046 | 0.79 | 0.81 | 83 | DMU |
| 3 | 862 | 0.78 | 0.81 | 59 | DMU |
| 4 | 685 | 0.72 | 0.79 | 59 | DMU |
| 5 | 291 | 0.56 | 0.76 | 54 | empty |
Interfaces
4 interfaces between chains.
- C–D · 1876 Ų buried · 27 hydrogen bonds · protein-protein
- A–B · 1774 Ų buried · 21 hydrogen bonds · protein-protein
- A–C · 893 Ų buried · 6 hydrogen bonds · protein-protein
- A–D · 328 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 5B0K · Structure of MoeN5-Sso7d fusion protein in complex with beta-decyl maltoside · the same entry in another collection · chain D against D, TM-score 1.00
- P39476 · AlphaFold monomer V2.0 prediction for DNA-binding protein 7D (P39476) · a predicted model of the same protein · chain D against A, TM-score 0.18
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A010
- Every structure of UniProt P39476
- Elsewhere: RCSB PDB 5B0K · PDBe 5B0K · UniProt A0A010 · UniProt P39476
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.