MolNFT v1 · #113932 · protein

Crystal structure of the SGIP1 mu homology domain in complex with an EPS15 fragment containing two dpf motifs (ydpfggdpfkg)

5AWT · SH3-containing GRB2-like protein 3-interacting protein 1: “Crystal structure of the SGIP1 mu homology domain in complex with an EPS15 fragment containing two dpf motifs…”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #113932 on…

PDB: 5AWT
Type: protein
Length: 276 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SH3-containing GRB2-like protein 3-interacting protein 1; Epidermal growth factor…
UniProt: Q9BQI5
Ligands: ZN

Structure

x-ray diffraction · 2 distinct chains · 12% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SH3-containing GRB2-like protein 3-interacting protein 1	protein	266	13% helix, 55% strand	Q9BQI5
B	Epidermal growth factor receptor substrate 15	protein	10	0% helix, 0% strand	—

Ligands and binding sites

ZN · Zinc ion · metal · 6 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 528 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

5AWT · Crystal structure of the SGIP1 mu homology domain in complex with an Eps15 fragment… · the same entry in another collection · chain A against A, TM-score 1.00
Q9BQI5 · AlphaFold monomer V2.0 prediction for SH3-containing GRB2-like protein 3-interacting… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9BQI5
Elsewhere: RCSB PDB 5AWT · PDBe 5AWT · UniProt Q9BQI5

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