MolNFT v1 · #113511 · protein
Imp-bound form of the D199N mutant of impdh from pseudomonas aeruginosa
5AHN · Inosine-5'-monophosphate dehydrogenase: “Imp-bound form of the D199N mutant of impdh from pseudomonas aeruginosa”. X-ray diffraction, 2 ligands (IMP, MG), 1 pocket (best druggability 0.53). MolNFT v1 #113511 on GenesisL1: 3D…
- PDB
- 5AHN
- Type
- protein
- Length
- 297 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Inosine-5'-monophosphate dehydrogenase
- EC
- 1.1.1.205
- UniProt
- Q9HXM5
- Ligands
- IMP, MG
- Pockets
- 1 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) | protein | 297 | 39% helix, 16% strand | Q9HXM5 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 242 | 0.53 | 0.76 | 30 | IMP |
Compared structures
- 5AHN · IMP-bound form of the D199N mutant of IMPDH from Pseudomonas aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HXM5
- Elsewhere: RCSB PDB 5AHN · PDBe 5AHN · UniProt Q9HXM5
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