MolNFT v1 · #113286 · protein
Optimization of a novel binding motif to to (E)-3-(3,5- difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2, 3,4,9-tetrahydro-1H-PYRIDO(3,4-B)INDOL-1-YL)PHENYL)ACRYLIC acid (AZD9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist
5AAV: “Optimization of a novel binding motif to to (E)-3-(3,5- difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-meth…”. X-ray diffraction. MolNFT v1 #113286 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5AAV
- Type
- protein
- Length
- 441 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03372
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 232 | — | P03372 |
| B | — | protein | 209 | — | P03372 |
Compared structures
- 5AAV · Optimization of a novel binding motif to to (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-m… · the same entry in another collection · chain A against A, TM-score 1.00
- P03372 · AlphaFold monomer V2.0 prediction for estrogen receptor (P03372) · a predicted model of the same protein · chain B against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03372
- Elsewhere: RCSB PDB 5AAV · PDBe 5AAV · UniProt P03372
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