MolNFT v1 · #112815 · protein

Crystal structure of the bacteriophage T4 recombination mediator protein uvsy, lattice type IV

4ZWT · Recombination protein uvsy: “Crystal structure of the bacteriophage T4 recombination mediator protein uvsy, lattice type IV”. X-ray diffraction, 20 pockets (best druggability 0.67). MolNFT v1 #112815 on GenesisL1: 3D structure…

PDB: 4ZWT
Type: protein
Length: 1,779 residues
Chains: 14
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Recombination protein uvsy
UniProt: P04537
Pockets: 20 · best druggability 0.67

Structure

x-ray diffraction · 11 distinct chains · 86% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Recombination protein uvsy	protein	121	90% helix, 0% strand	P04537
B	Recombination protein uvsy	protein	126	85% helix, 0% strand	P04537
C	Recombination protein uvsy	protein	134	81% helix, 1% strand	P04537
D, I, K	Recombination protein uvsy	protein	128	86% helix, 0% strand	P04537
E, L	Recombination protein uvsy	protein	126	87% helix, 0% strand	P04537
F	Recombination protein uvsy	protein	125	90% helix, 0% strand	P04537
G	Recombination protein uvsy	protein	127	87% helix, 0% strand	P04537
H	Recombination protein uvsy	protein	127	89% helix, 0% strand	P04537
J	Recombination protein uvsy	protein	135	81% helix, 1% strand	P04537
M	Recombination protein uvsy	protein	123	89% helix, 0% strand	P04537
N	Recombination protein uvsy	protein	125	85% helix, 0% strand	P04537

Pockets

20 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	796	0.67	0.75	74	empty
2	119	0.66	0.89	26	empty
3	129	0.51	0.80	30	empty
4	101	0.51	0.82	25	empty
5	93	0.51	0.83	23	empty

Interfaces

22 interfaces between chains.

F–G · 1135 Å² buried · 4 hydrogen bonds · protein-protein
H–I · 1124 Å² buried · 6 hydrogen bonds · protein-protein
I–J · 1112 Å² buried · 3 hydrogen bonds · protein-protein
J–K · 1089 Å² buried · 6 hydrogen bonds · protein-protein
D–E · 1066 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

4ZWT · Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04537
Elsewhere: RCSB PDB 4ZWT · PDBe 4ZWT · UniProt P04537

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