Research workbench

Crystal structure of the bacteriophage T4 recombination mediator protein uvsy, lattice type IV

Analyse Crystal structure of the bacteriophage T4 recombination mediator protein uvsy… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4ZWT
Type: protein
Length: 1,779 residues
Chains: 14
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Recombination protein uvsy
UniProt: P04537
Pockets: 20 · best druggability 0.67

Structure

x-ray diffraction · 11 distinct chains · 86% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Recombination protein uvsy	protein	121	90% helix, 0% strand	P04537
B	Recombination protein uvsy	protein	126	85% helix, 0% strand	P04537
C	Recombination protein uvsy	protein	134	81% helix, 1% strand	P04537
D, I, K	Recombination protein uvsy	protein	128	86% helix, 0% strand	P04537
E, L	Recombination protein uvsy	protein	126	87% helix, 0% strand	P04537
F	Recombination protein uvsy	protein	125	90% helix, 0% strand	P04537
G	Recombination protein uvsy	protein	127	87% helix, 0% strand	P04537
H	Recombination protein uvsy	protein	127	89% helix, 0% strand	P04537
J	Recombination protein uvsy	protein	135	81% helix, 1% strand	P04537
M	Recombination protein uvsy	protein	123	89% helix, 0% strand	P04537
N	Recombination protein uvsy	protein	125	85% helix, 0% strand	P04537

Pockets

20 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	796	0.67	0.75	74	empty
2	119	0.66	0.89	26	empty
3	129	0.51	0.80	30	empty
4	101	0.51	0.82	25	empty
5	93	0.51	0.83	23	empty

Interfaces

22 interfaces between chains.

F–G · 1135 Å² buried · 4 hydrogen bonds · protein-protein
H–I · 1124 Å² buried · 6 hydrogen bonds · protein-protein
I–J · 1112 Å² buried · 3 hydrogen bonds · protein-protein
J–K · 1089 Å² buried · 6 hydrogen bonds · protein-protein
D–E · 1066 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

4ZWT · Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04537
Elsewhere: RCSB PDB 4ZWT · PDBe 4ZWT · UniProt P04537

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.