MolNFT v1 · #112357 · protein
Crystal structure of native alpha-2-macroglobulin from escherichia COLI spanning the residues from domain MG7 to the C-terminus.
4ZIU · Uncharacterized lipoprotein yfhm: “Crystal structure of native alpha-2-macroglobulin from escherichia COLI spanning the residues from domain MG7…”. X-ray diffraction, 1 ligand (NI), 6 pockets (best druggability 0.79). MolNFT v1…
- PDB
- 4ZIU
- Type
- protein
- Length
- 639 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized lipoprotein yfhm
- UniProt
- P76578
- Ligands
- NI
- Pockets
- 6 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized lipoprotein yfhm | protein | 639 | 30% helix, 31% strand | P76578 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 752 | 0.79 | 0.83 | 69 | empty |
| 2 | 202 | 0.70 | 0.87 | 32 | empty |
| 3 | 149 | 0.60 | 0.84 | 25 | empty |
| 4 | 94 | 0.59 | 0.87 | 22 | empty |
| 5 | 191 | 0.54 | 0.79 | 27 | empty |
Compared structures
- 4ZIU · Crystal structure of native alpha-2-macroglobulin from Escherichia coli spanning the… · the same entry in another collection · chain A against A, TM-score 1.00
- P76578 · AlphaFold monomer V2.0 prediction for alpha-2-macroglobulin (P76578) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P76578
- Elsewhere: RCSB PDB 4ZIU · PDBe 4ZIU · UniProt P76578
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