MolNFT v1 · #112316 · protein + DNA
Crystal structure of alkb T208A mutant protein in complex with CO(II), 2-oxoglutarate, and methylated trinucleotide T-mea-T
4ZHN · Methylated trinucleotide DNA T-mea-T: “Crystal structure of alkb T208A mutant protein in complex with CO(II), 2-oxoglutarate, and methylated…”. X-ray diffraction, 2 ligands (AKG, CO). MolNFT v1 #112316 on GenesisL1: 3D structure…
- PDB
- 4ZHN
- Type
- protein + DNA
- Length
- 203 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methylated trinucleotide DNA T-mea-T; Alpha-ketoglutarate-dependent dioxygenase alkb
- EC
- 1.14.11.33
- UniProt
- P05050
- Ligands
- AKG, CO
Structure
x-ray diffraction · 2 distinct chains · 15% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Methylated trinucleotide DNA T-mea-T | dna | 3 | — | — |
| A | Alpha-ketoglutarate-dependent dioxygenase alkb (EC 1.14.11.33) | protein | 200 | 15% helix, 35% strand | P05050 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- B–A · 540 Ų buried · 10 hydrogen bonds · protein-nucleic
Modifications
Observed in the structure: 1 modified (nucleotide modification).
Compared structures
- 4ZHN · Crystal Structure of AlkB T208A mutant protein in complex with Co(II), 2-oxoglutarate… · the same entry in another collection · chain B against B, TM-score 1.00
- P05050 · AlphaFold monomer V2.0 prediction for alpha-ketoglutarate-dependent dioxygenase alkb… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05050
- Elsewhere: RCSB PDB 4ZHN · PDBe 4ZHN · UniProt P05050
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