MolNFT v1 · #112314 · protein
The crystal structure of mupain-1-ig in complex with murinised human upa at PH7.4
4ZHL · Urokinase-type plasminogen activator: “The crystal structure of mupain-1-ig in complex with murinised human upa at PH7.4”. X-ray diffraction. MolNFT v1 #112314 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4ZHL
- Type
- protein
- Length
- 257 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Urokinase-type plasminogen activator; Mupain-1-ig
- EC
- 3.4.21.73
- UniProt
- P00749
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| U | Urokinase-type plasminogen activator (EC 3.4.21.73) | protein | 247 | 11% helix, 40% strand | P00749 |
| P | Mupain-1-ig | protein | 10 | 0% helix, 10% strand | — |
Interfaces
1 interface between chains.
- U–P · 757 Ų buried · 21 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 4ZHL · The crystal structure of mupain-1-IG in complex with murinised human uPA at pH7.4 · the same entry in another collection · chain U against U, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00749
- Elsewhere: RCSB PDB 4ZHL · PDBe 4ZHL · UniProt P00749
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