MolNFT v1 · #111574 · protein

Crystal structure of photoactivated adenylyl cyclase of a cyanobacteriaoscillatoria acuminata in hexagonal form

4YUS · Family 3 adenylate cyclase: “Crystal structure of photoactivated adenylyl cyclase of a cyanobacteriaoscillatoria acuminata in hexagonal…”. X-ray diffraction, 1 ligand (FMN), 4 pockets (best druggability 0.61). MolNFT v1 #111574 on…

PDB: 4YUS
Type: protein
Length: 350 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Family 3 adenylate cyclase
EC: 4.6.1.1
UniProt: K9TLZ5
Ligands: FMN
Pockets: 4 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Family 3 adenylate cyclase (EC 4.6.1.1)	protein	350	44% helix, 30% strand	K9TLZ5

Ligands and binding sites

FMN · Flavin mononucleotide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	139	0.61	0.85	20	FMN
2	106	0.48	0.80	23	empty
3	90	0.35	0.74	20	empty
4	86	0.34	0.75	15	empty

Compared structures

4YUS · Crystal structure of photoactivated adenylyl cyclase of a cyanobacteriaOscillatoria… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt K9TLZ5
Elsewhere: RCSB PDB 4YUS · PDBe 4YUS · UniProt K9TLZ5

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