MolNFT v1 · #111072 · protein
Structure of the synthetic duffy binding protein (dbp) antigen deknull relevant for malaria vaccine design
4YFS · Duffy receptor: “Structure of the synthetic duffy binding protein (dbp) antigen deknull relevant for malaria vaccine design”. X-ray diffraction, 3 pockets (best druggability 0.72). MolNFT v1 #111072 on GenesisL1: 3D structure…
- PDB
- 4YFS
- Type
- protein
- Length
- 285 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Duffy receptor
- UniProt
- P22290
- Pockets
- 3 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 67% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Duffy receptor | protein | 285 | 67% helix, 1% strand | P22290 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 92 | 0.72 | 0.95 | 22 | empty |
| 2 | 73 | 0.34 | 0.75 | 17 | empty |
| 3 | 62 | 0.29 | 0.74 | 16 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 4YFS · Structure of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for… · the same entry in another collection · chain A against A, TM-score 1.00
- P22290 · AlphaFold monomer V2.0 prediction for duffy receptor (P22290) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22290
- Elsewhere: RCSB PDB 4YFS · PDBe 4YFS · UniProt P22290
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