MolNFT v1 · #110519 · protein

The crystal structure of kupe virus nucleoprotein

4XZC: “The crystal structure of kupe virus nucleoprotein”. X-ray diffraction, 7 pockets (best druggability 0.82). MolNFT v1 #110519 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4XZC
Type: protein
Length: 933 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleoprotein
UniProt: B8PWH3
Pockets: 7 · best druggability 0.82

Structure

x-ray diffraction · 2 distinct chains · 59% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoprotein	protein	468	60% helix, 4% strand	B8PWH3
B	Nucleoprotein	protein	465	58% helix, 2% strand	B8PWH3

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	994	0.82	0.83	73	empty
2	933	0.79	0.81	70	empty
3	172	0.48	0.77	27	empty
4	194	0.48	0.75	22	empty
5	154	0.48	0.77	20	empty

Interfaces

1 interface between chains.

A–B · 51 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

4XZC · The crystal structure of Kupe virus nucleoprotein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B8PWH3
Elsewhere: RCSB PDB 4XZC · PDBe 4XZC · UniProt B8PWH3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.