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MolNFT v1 · #110280 · protein + DNA

Heterodimeric complex of transcription factors MEIS1 and DLX3 on specific DNA

4XRS: “Heterodimeric complex of transcription factors MEIS1 and DLX3 on specific DNA”. X-ray diffraction. MolNFT v1 #110280 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
4XRS
Type
protein + DNA
Length
292 residues
Chains
8
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
O00470, O60479

Structure

x-ray diffraction · 7 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
M—dna15——
D—dna17——
E—dna18——
L—dna16——
A—protein56—O00470
B—protein58—O00470
G, I—protein56—O60479

Compared structures

  • 4XRS · Heterodimeric complex of transcription factors MEIS1 and DLX3 on specific DNA · the same entry in another collection · chain I against I, TM-score 1.00
  • O00470 · AlphaFold monomer V2.0 prediction for homeobox protein MEIS1 (O00470) · a predicted model of the same protein · chain A against A, TM-score 0.75
  • O60479 · AlphaFold monomer V2.0 prediction for homeobox protein dlx-3 (O60479) · a predicted model of the same protein · chain G against A, TM-score 0.67

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