MolNFT v1 · #110272 · protein
Crystal structure of importin beta in a polyethylene glycol condition
4XRK: “Crystal structure of importin beta in a polyethylene glycol condition”. X-ray diffraction, 7 pockets (best druggability 0.61). MolNFT v1 #110272 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4XRK
- Type
- protein
- Length
- 832 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Importin beta
- UniProt
- G0S143
- Pockets
- 7 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Importin beta | protein | 832 | 74% helix, 0% strand | G0S143 |
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 346 | 0.61 | 0.78 | 24 | empty |
| 2 | 67 | 0.46 | 0.82 | 15 | empty |
| 3 | 162 | 0.45 | 0.75 | 20 | empty |
| 4 | 100 | 0.41 | 0.77 | 16 | empty |
| 5 | 64 | 0.34 | 0.76 | 11 | empty |
Compared structures
- 4XRK · Crystal Structure of Importin Beta in a Polyethylene Glycol Condition · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0S143
- Elsewhere: RCSB PDB 4XRK · PDBe 4XRK · UniProt G0S143
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