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Crystal structure of importin beta in a polyethylene glycol condition

Analyse Crystal structure of importin beta in a polyethylene glycol condition in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4XRK
Type
protein
Length
832 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Importin beta
UniProt
G0S143
Pockets
7 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AImportin betaprotein83274% helix, 0% strandG0S143

Pockets

7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13460.610.7824empty
2670.460.8215empty
31620.450.7520empty
41000.410.7716empty
5640.340.7611empty

Compared structures

  • 4XRK · Crystal Structure of Importin Beta in a Polyethylene Glycol Condition · the same entry in another collection · chain A against A, TM-score 1.00

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