MolNFT v1 · #109904 · protein
Structure of the nuclease subunit of human mitochondrial RNase P (MRPP3) at 1.8A
4XGL · Mitochondrial ribonuclease P protein 3: “Structure of the nuclease subunit of human mitochondrial RNase P (MRPP3) at 1.8A”. X-ray diffraction, 1 ligand (ZN), 3 pockets (best druggability 0.57). MolNFT v1 #109904 on GenesisL1: 3D…
- PDB
- 4XGL
- Type
- protein
- Length
- 342 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mitochondrial ribonuclease P protein 3
- EC
- 3.1.26.5
- UniProt
- O15091
- Ligands
- ZN
- Pockets
- 3 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitochondrial ribonuclease P protein 3 (EC 3.1.26.5) | protein | 342 | 48% helix, 15% strand | O15091 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 209 | 0.57 | 0.80 | 38 | empty |
| 2 | 60 | 0.40 | 0.80 | 14 | empty |
| 3 | 54 | 0.31 | 0.76 | 18 | empty |
Compared structures
- 4XGL · Structure of the nuclease subunit of human mitochondrial RNase P (MRPP3) at 1.8A · the same entry in another collection · chain A against A, TM-score 1.00
- O15091 · AlphaFold monomer V2.0 prediction for mitochondrial ribonuclease P catalytic subunit… · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15091
- Elsewhere: RCSB PDB 4XGL · PDBe 4XGL · UniProt O15091
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