MolNFT v1 · #244230 · protein
AlphaFold monomer V2.0 prediction for mitochondrial ribonuclease P catalytic subunit (O15091)
O15091: “AlphaFold monomer V2.0 prediction for mitochondrial ribonuclease P catalytic subunit (O15091)”. 2 pockets (best druggability 0.75). MolNFT v1 #244230 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O15091
- Type
- protein
- Length
- 583 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1ad771C934EF56ebFF74f7581CB73023aCA831d3
- Molecule
- Mitochondrial ribonuclease P catalytic subunit
- UniProt
- O15091
- Pockets
- 2 · best druggability 0.75
Structure
1 distinct chain · 44% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitochondrial ribonuclease P catalytic subunit | protein | 583 | 44% helix, 9% strand | O15091 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 981 | 0.75 | 0.77 | 80 | empty |
| 2 | 139 | 0.48 | 0.78 | 16 | empty |
Compared structures
- 7ONU · Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-tyr · an experimental structure of the same protein · chain A against E, TM-score 0.64
- 7ONU · Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-Tyr · an experimental structure of the same protein · chain A against E, TM-score 0.64
- 8CBK · Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-His(5,Ser) · an experimental structure of the same protein · chain A against E, TM-score 0.61
- 4XGL · Structure of the nuclease subunit of human mitochondrial RNase P (MRPP3) at 1.8A · an experimental structure of the same protein · chain A against A, TM-score 0.58
- 4XGL · Structure of the nuclease subunit of human mitochondrial RNase P (MRPP3) at 1.8A · an experimental structure of the same protein · chain A against A, TM-score 0.58
- 4XGM · Structure of the nuclease subunit of human mitochondrial RNase P (MRPP3) at 1.98A · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 4XGM · Structure of the nuclease subunit of human mitochondrial RNase P (MRPP3) at 1.98A · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 4ROU · Auto-inhibition mechanism of human mitochondrial RNase P protein complex · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 4ROU · Auto-inhibition Mechanism of Human Mitochondrial RNase P Protein Complex · an experimental structure of the same protein · chain A against A, TM-score 0.43
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15091
- Elsewhere: UniProt O15091 · AlphaFold DB O15091
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