MolNFT v1 · #109813 · protein

Crystal structure of treponema pallidum TP0796 flavin trafficking protein, a bifunctional FMN TRANSFERASE/FAD pyrophosphatase, N55Y mutant, FAD bound form

4XDT · FAD:PROTEIN FMN transferase: “Crystal structure of treponema pallidum TP0796 flavin trafficking protein, a bifunctional FMN TRANSFERASE/FAD…”. X-ray diffraction, 3 ligands (FAD, MG, NA), 2 pockets (best druggability 0.76). MolNFT v1…

PDB: 4XDT
Type: protein
Length: 330 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: FAD:PROTEIN FMN transferase
EC: 2.7.1.180
UniProt: O83774
Ligands: FAD, MG, NA
Pockets: 2 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	FAD:PROTEIN FMN transferase (EC 2.7.1.180)	protein	330	34% helix, 29% strand	O83774

Ligands and binding sites

FAD · Flavin-adenine dinucleotide · ligand · chains A
MG · Magnesium ion · metal · 2 copies · chains A
NA · Sodium ion · metal · 2 copies · chains A
EDO · 1,2-ethanediol · additive · 5 copies · chains A
ACT · Acetate ion · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	637	0.76	0.82	73	FAD, MG, ACT
2	53	0.29	0.75	13	empty

Compared structures

4XDT · Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, a bifunctional… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O83774
Elsewhere: RCSB PDB 4XDT · PDBe 4XDT · UniProt O83774

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