MolNFT v1 · #109627 · protein

Crystal structure of E. COLI adenylate kinase P177A mutant

4X8H: “Crystal structure of E. COLI adenylate kinase P177A mutant”. X-ray diffraction, 2 pockets (best druggability 0.48). MolNFT v1 #109627 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4X8H
Type: protein
Length: 214 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Adenylate kinase
EC: 2.7.4.3
UniProt: P69441
Pockets: 2 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Adenylate kinase (EC 2.7.4.3)	protein	214	50% helix, 17% strand	P69441

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	56	0.48	0.85	13	empty
2	63	0.35	0.77	15	empty

Compared structures

4X8H · Crystal structure of E. coli Adenylate kinase P177A mutant · the same entry in another collection · chain A against A, TM-score 1.00
P69441 · AlphaFold monomer V2.0 prediction for adenylate kinase (P69441) · a predicted model of the same protein · chain A against A, TM-score 0.69

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P69441
Elsewhere: RCSB PDB 4X8H · PDBe 4X8H · UniProt P69441

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.