UniProt P69441
Adenylate kinase (P69441)
Adenylate kinase (UniProt P69441), EC 2.7.4.3: 28 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P69441
- Protein
- Adenylate kinase
- EC
- 2.7.4.3
- Experimental structures
- 28
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 19 · 3 records with a druggable one
Structures
29 records of P69441 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AKE | Structure of the complex between adenylate kinase from escherichia COLI and the inhibitor AP5A… | x-ray diffraction | A, B | — | — |
| 1AKE | Structure of the complex between adenylate kinase from escherichia COLI and the inhibitor AP5A… | x-ray diffraction | A, B | — | — |
| 1E4V | Mutant G10V of adenylate kinase from E. coli, modified in the Gly-loop | x-ray diffraction | A, B | — | — |
| 1E4V | Mutant G10V of adenylate kinase from E. COLI, modified in the gly-loop | x-ray diffraction | A, B | — | — |
| 1E4Y | Mutant P9L of adenylate kinase from E. coli, modified in the Gly-loop | x-ray diffraction | A, B | — | — |
| 1E4Y | Mutant P9L of adenylate kinase from E. COLI, modified in the gly-loop | x-ray diffraction | A, B | — | — |
| 2ECK | Structure of phosphotransferase | x-ray diffraction | A, B | — | — |
| 2ECK | Structure of phosphotransferase | x-ray diffraction | A, B | — | — |
| 3HPQ | Crystal structure of wild-type adenylate kinase from E. coli, in complex with Ap5A | x-ray diffraction | A, B | — | — |
| 3HPQ | Crystal structure of wild-type adenylate kinase from E. COLI, in complex with AP5A | x-ray diffraction | A, B | — | — |
| 3HPR | Crystal structure of V148G adenylate kinase from E. coli, in complex with Ap5A | x-ray diffraction | A, B | — | — |
| 3HPR | Crystal structure of V148G adenylate kinase from E. COLI, in complex with AP5A | x-ray diffraction | A, B | — | — |
| 4AKE | Adenylate kinase | x-ray diffraction | A, B | — | — |
| 4AKE | Adenylate kinase | x-ray diffraction | A, B | — | — |
| 4X8H | Crystal structure of E. coli Adenylate kinase P177A mutant | x-ray diffraction | A | — | — |
| 4X8H | Crystal structure of E. COLI adenylate kinase P177A mutant | x-ray diffraction | A | — | — |
| 4X8L | Crystal structure of E. coli Adenylate kinase P177A mutant in complex with inhibitor Ap5a | x-ray diffraction | A, B | — | — |
| 4X8L | Crystal structure of E. COLI adenylate kinase P177A mutant in complex with inhibitor AP5A | x-ray diffraction | A, B | — | — |
| 4X8M | Crystal structure of E. coli Adenylate kinase Y171W mutant | x-ray diffraction | A | — | — |
| 4X8M | Crystal structure of E. COLI adenylate kinase Y171W mutant | x-ray diffraction | A | — | — |
| 4X8O | Crystal structure of E. coli Adenylate kinase Y171W mutant in complex with inhibitor Ap5a | x-ray diffraction | A, B | — | — |
| 4X8O | Crystal structure of E. COLI adenylate kinase Y171W mutant in complex with inhibitor AP5A | x-ray diffraction | A, B | — | — |
| 6HAM | Adenylate kinase | x-ray diffraction | A | AP5 | — |
| 6HAM | Adenylate kinase | x-ray diffraction | A | AP5 | — |
| 7APU | Structure of Adenylate kinase from Escherichia coli in complex with two ADP molecules refined at… | x-ray diffraction | A, B | ADP, NA | 4 (best 0.82) |
| 7APU | Structure of adenylate kinase from escherichia COLI in complex with two ADP molecules refined at… | x-ray diffraction | A, B | ADP, NA | — |
| 8CRG | E. coli adenylate kinase in complex with two ADP molecules as a result of enzymatic AP4A hydrolysis | x-ray diffraction | A, B | ADP | 3 (best 0.83) |
| 8RJ4 | E. coli adenylate kinase in complex with two ADP molecules and Mg2+ as a result of enzymatic AP4A… | x-ray diffraction | A, B, C, D | ADP, MG, CL | 12 (best 0.81) |
| P69441 | AlphaFold monomer V2.0 prediction for adenylate kinase (P69441) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7APU chain A against the predicted model P69441: TM-score 0.99, RMSD 0.65 Å
- 7APU chain A against the predicted model P69441: TM-score 0.99, RMSD 0.65 Å
- 4X8O chain A against the predicted model P69441: TM-score 0.99, RMSD 0.67 Å
- 4X8O chain A against the predicted model P69441: TM-score 0.99, RMSD 0.67 Å
- 4X8L chain A against the predicted model P69441: TM-score 0.99, RMSD 0.68 Å
- 4X8L chain A against the predicted model P69441: TM-score 0.99, RMSD 0.68 Å
- 2ECK chain A against the predicted model P69441: TM-score 0.99, RMSD 0.70 Å
- 2ECK chain A against the predicted model P69441: TM-score 0.99, RMSD 0.70 Å
- 7APU chain B against the predicted model P69441: TM-score 0.98, RMSD 0.75 Å
- 1AKE chain A against the predicted model P69441: TM-score 0.98, RMSD 0.75 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.