MolNFT v1 · #109066 · protein
Crystal structure of surfactant protein-a dedn mutant (E171D/P175E/R197N/K203D)
4WRC · Pulmonary surfactant-associated protein a: “Crystal structure of surfactant protein-a dedn mutant (E171D/P175E/R197N/K203D)”. X-ray diffraction, 2 ligands (CA, CL). MolNFT v1 #109066 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4WRC
- Type
- protein
- Length
- 140 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pulmonary surfactant-associated protein a
- UniProt
- P08427
- Ligands
- CA, CL
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pulmonary surfactant-associated protein a | protein | 140 | 29% helix, 28% strand | P08427 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A
- CL · Chloride ion · ion · chains A
- HEZ · Hexane-1,6-diol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 4WRC · Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D) · the same entry in another collection · chain A against A, TM-score 1.00
- P08427 · AlphaFold monomer V2.0 prediction for pulmonary surfactant-associated protein a (P08427) · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08427
- Elsewhere: RCSB PDB 4WRC · PDBe 4WRC · UniProt P08427
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