MolNFT v1 · #10904 · protein
Crystal structure of transcriptional regulator (TM1602) from thermotoga maritima at 2.3 a resolution
1J5Y · Transcriptional regulator, biotin repressor family: “Crystal structure of transcriptional regulator (TM1602) from thermotoga maritima at 2.3 a resolution”. X-ray diffraction, 2 ligands (NI, K), 2 pockets (best druggability 0.48).…
- PDB
- 1J5Y
- Type
- protein
- Length
- 172 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator, biotin repressor family
- UniProt
- Q9X1T8
- Ligands
- NI, K
- Pockets
- 2 · best druggability 0.48
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator, biotin repressor family | protein | 172 | 48% helix, 24% strand | Q9X1T8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 124 | 0.48 | 0.79 | 19 | empty |
| 2 | 63 | 0.33 | 0.76 | 12 | empty |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 1J5Y · Crystal structure of transcriptional regulator (TM1602) from Thermotoga maritima at 2.3 A… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9X1T8 · AlphaFold monomer V2.0 prediction for probable transcription repressor niar (Q9X1T8) · a predicted model of the same protein · chain A against A, TM-score 0.77
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X1T8
- Elsewhere: RCSB PDB 1J5Y · PDBe 1J5Y · UniProt Q9X1T8
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